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Imikhiqizo-isibhengezo

Imikhiqizo

I-Lifecosm CHW Ag/Anaplasma Ab/E.canis Ab/LSH Ikhithi Yokuhlola ye-Ab Umuthi wezilwane Isithombe Esifakiwe
  • I-Lifecosm CHW Ag/Anaplasma Ab/E.canis Ab/LSH Ikhithi Yokuhlola ye-Ab Umuthi wezilwane
  • I-Lifecosm CHW Ag/Anaplasma Ab/E.canis Ab/LSH Ikhithi Yokuhlola ye-Ab Umuthi wezilwane
  • I-Lifecosm CHW Ag/Anaplasma Ab/E.canis Ab/LSH Ikhithi Yokuhlola ye-Ab Umuthi wezilwane

I-Lifecosm CHW Ag/Anaplasma Ab/E.canis Ab/LSH Ikhithi Yokuhlola ye-Ab Umuthi wezilwane

Ikhodi yomkhiqizo: RC-CF31

Igama lento: Canine Heartworm Ag/Anaplasma Ab/Ehrlichia canis Ab/Leishmania Ab test kit

Inombolo yekhathalogi: RC-CF31

Isifinyezo:Ukutholwa kwama-antigens eCanine Dirofilaria immitis, amasosha omzimba e-Anaplasma, amasosha omzimba e-E. canis kanye namasosha omzimba e-LSH phakathi nemizuzu eyi-10

Isimiso: Isinyathelo esisodwa sokuhlolwa kwe-immunochromatographic

Okuhloswe ngakho:

CHW Ag : Dirofilaria immititis antigens Anapalsma Ab : Amasosha omzimba e-Anaplasma

E. canis Ab : Amasosha omzimba E. canis

LSH Ab : L. chagasi, L. infantum, kanye no-L. donovani

amagciwane

Isampula: I-Canine Whole Blood, i-Plasma noma iSerum

Isikhathi sokufunda: 10 ~ 15 imizuzu

Isitoreji: Ithempelesha Yegumbi (ku-2 ~ 30℃)

Ukuphelelwa yisikhathi: Izinyanga ezingama-24 ngemuva kokukhiqiza


IKHATHALOGU

Imininingwane Yomkhiqizo

Omaka bomkhiqizo

I-CHW Ag/Anaplasma Ab/E.canis Ab/LSH Ab Ikhithi Yokuhlola I-Canine Heartworm Ag/Anaplasma Ab /Ehrlichia canis Ab/Leishmania Ab Ikhithi yokuhlola

Inombolo yekhathalogi I-RC-CF31
 Isifinyezo

Ukutholwa kwama-Canine Dirofilaria immitis antigens, amasosha omzimba e-Anaplasma, amasosha omzimba e-E. canis kanye namasosha omzimba e-LSH phakathi nemizuzu eyi-10
Isimiso Isinyathelo esisodwa sokuhlolwa kwe-immunochromatographic
 Okuhloswe ngakho Ukuthola CHW Ag : Dirofilaria immititis antigens Anapalsma Ab : Amasosha omzimba e-AnaplasmaE. canis Ab : Amasosha omzimba E. canis

LSH Ab : L. chagasi, L. infantum, kanye no-L. donovani

amagciwane
Isampula I-Canine Igazi Eliphelele, I-Plasma noma I-Serum
Isikhathi sokufunda Imizuzu eyi-10
 
Ubuningi Ibhokisi elingu-1 (ikhithi) = amadivaysi ayi-10 (Ukupakishwa komuntu ngamunye)
Okuqukethwe Ikhithi yokuhlola, ibhodlela le-Buffer, kanye ne-dropper elahlayo
Isitoreji Ithempelesha Yegumbi (ku-2 ~ 30℃)
Ukuphelelwa yisikhathi Izinyanga ezingama-24 ngemuva kokukhiqiza
  

Isexwayiso

 Sebenzisa phakathi kwemizuzu eyi-10 ngemuva kokuvulaSebenzisa inani elifanele lesampula (0.01 ml ye-dropper)

Sebenzisa ngemva kwemizuzu engu-15–30 e-RT uma egcinwe ngaphansi kwezimo ezibandayo

Cabangela imiphumela yokuhlolwa njengengavumelekile ngemva kwemizuzu engu-10

Ulwazi

Izikelemu zenhliziyo zabantu abadala zikhula ngamasentimitha ambalwa ubude futhi zihlala emithanjeni yamaphaphu lapho zingathola khona imisoco eyanele.Izikelemu zenhliziyo ngaphakathi emithanjeni zibangela ukuvuvukala futhi zenze i-hematoma.Inhliziyo-ke kufanele iphampe kaningi kunangaphambili njengoba izikelemu zenhliziyo zanda ngenani, zivale imithambo.

Uma ukutheleleka kukhula (ngaphezu kwama-heartworms angu-25 enja engu-18 kg), izikelemu zenhliziyo zingena ku-atrium engakwesokudla, zivimbe ukugeleza kwegazi.

Lapho inani lama-heartworms lifinyelela ngaphezu kwama-50, bangahlala

ama-atrium nama-ventricles.

Lapho itheleleka ngezikelemu zenhliziyo ezingaphezu kwe-100 engxenyeni efanele yenhliziyo, inja ilahlekelwa ukusebenza kwenhliziyo futhi ekugcineni iyafa.Lokhu kuyabulala

I-phenomenon ibizwa ngokuthi "i-Caval Syndrom."

Ngokungafani nezinye izilokazane, izikelemu zenhliziyo zibeka izinambuzane ezincane ezibizwa ngokuthi i-microfilaria.I-Microfilaria kumiyane ingena enjeni lapho umiyane umunca igazi enjeni.Ama-heartworms angaphila kumphathi iminyaka engu-2 ayafa uma engathutheli komunye umsingathi phakathi naleso sikhathi.Amagciwane ahlala enjeni ekhulelwe angakwazi ukuthelela umbungu wayo.

Ukuhlolwa kusenesikhathi kwezikelemu zenhliziyo kubaluleke kakhulu ekuziqedeni.Izikelemu zenhliziyo zidlula ezinyathelweni ezimbalwa ezifana ne-L1, L2, L3 kuhlanganise nesiteji sokudlulisela ngomiyane ukuze zibe izikelemu zenhliziyo zabantu abadala.

Izikelemu zomiyane

I-Microfilaria kumiyane ikhula ibe izimuncagazi ze-L2 kanye ne-L3 ezikwazi ukuthelela izinja emasontweni ambalwa.Ukukhula kuncike esimweni sezulu.Izinga lokushisa elilungile le-parasite lingaphezu kuka-13.9 ℃.

Lapho umiyane onaleli gciwane luluma inja, i-microfilaria ye-L3 ingena esikhunjeni sayo.Esikhumbeni, i-microfilaria ikhula ibe yi-L4 amaviki angu-1 ~ 2.Ngemva kokuhlala esikhumbeni izinyanga ezi-3, i-L4 ikhula ibe yi-L5, engena egazini.

I-L5 njengohlobo lwe-heartworm yabantu abadala ingena enhliziyweni nasemithanjeni yamaphaphu lapho ezinyangeni ezingu-5 ~ 7 kamuva izikelemu zenhliziyo zibeka izinambuzane.

123cb (2) - 副本
123cb (1)

Ukuxilongwa

Umlando wesifo kanye nedatha yomtholampilo yenja egulayo, nezindlela ezihlukahlukene zokuxilonga kufanele zicatshangelwe ekuxilongeni inja.Isibonelo, i-X-ray, i-ultrasound scan, ukuhlolwa kwegazi, ukutholakala kwe-microfilaria futhi, esimweni esibi kakhulu, ukuhlolwa kwe-autopsy kuyadingeka.

Ukuhlolwa kweSerum;

Ukutholwa kwamasosha omzimba noma ama-antigens egazini

Ukuhlolwa kwe-Antigen;

Lokhu kugxile ekutholeni ama-antigen athile ezikelemu zenhliziyo zabantu besifazane.Ukuhlolwa kwenziwa esibhedlela futhi izinga layo lokuphumelela liphezulu.Amakhithi okuhlola atholakala emakethe aklanyelwe ukuthola izikelemu zenhliziyo zabantu abadala ezinezinyanga ezingu-7~8 ukuze kube nzima ukuzibona izikelemu zenhliziyo ezingaphansi kwezinyanga ezi-5.

Ukwelashwa

Ukutheleleka kwe-heartworms kwelapheka ngempumelelo ezimweni eziningi.Ukuqeda zonke izikelemu zenhliziyo, ukusetshenziswa kwemithi kuyindlela engcono kakhulu.Ukutholwa kusenesikhathi kwezikelemu zenhliziyo kuphakamisa izinga lempumelelo yokwelashwa.Kodwa-ke, esigabeni sokugcina sokutheleleka, kungenzeka kube nezinkinga, okwenza ukwelashwa kube nzima kakhulu.

Ulwazi

Ibhaktheriya i-Anaplasma phagocytophilum (ngaphambilini eyayaziwa ngokuthi i-Ehrilichia phagocytophila) ingase ibangele ukutheleleka ezinhlobonhlobo zezilwane eziningana kuhlanganise nabantu.Lesi sifo esitholakala ezilwaneni ezifuywayo sibizwa nangokuthi i-tick-borne fever (TBF), futhi saziwa okungenani iminyaka engu-200.Amagciwane omndeni wakwa-Anaplasmataceae ayi-gram-negative, nonmotile, i-coccoid kuya ku-ellipsoid organisms, ahluka ngosayizi ukusuka ku-0.2 kuya ku-2.0um ububanzi.Ziyi-aerobes ephoqelekile, ayinayo indlela ye-glycolytic, futhi zonke ziyizilokazane ze-intracellular.Zonke izinhlobo zezinhlobo ze-Anaplasma zihlala kuma-vacuoles ane-membrane-lined kumaseli angakakhuli noma avuthiwe e-hematopoietic host host mammalian.I-phagocytophilum ihlasela ama-neutrophils kanti igama elithi granulocytotropic libhekisela kuma-neutrophils angenwe yileli gciwane.Izinto eziphilayo ezingavamile, ziye zatholakala kuma-eosinophils.

I-Anaplasma phagocytophilum

Izimpawu

Izimpawu zomtholampilo ezijwayelekile zeI-canine anaplasmosis ihlanganisa ukushisa okukhulu, ukukhathala, ukucindezeleka kanye ne-polyarthritis.Izimpawu ze-neurologic (ataxia, seizures kanye nobuhlungu bentamo) nazo zingabonakala.Ukutheleleka kwe-Anaplasma phagocytophilum akuvamile ukubulawa ngaphandle uma kuyinkimbinkimbi ngezinye izifo.Ukulahlekelwa okuqondile, izimo ezikhubazekile kanye nokulahlekelwa kokukhiqiza kuye kwabonwa emazinyaneni.Ukukhipha isisu kanye ne-spermatogenesis ekhubazekile ezimvini nasezinkomeni kubhaliwe.Ubunzima bokutheleleka buthonywa izici ezimbalwa, njengokuhlukahluka kwe-Anaplasma phagocytophilum ehilelekile, amanye amagciwane, ubudala, isimo sokuzivikela komzimba nesimo somsingathi, nezici ezifana nesimo sezulu nokuphathwa.Kufanele kukhulunywe ukuthi ukubonakaliswa komtholampilo kubantu kusuka ekuguleni okuncane okuzikhawulele okufana nomkhuhlane, kuya ekuthelelekeni okusongela ukuphila.Kodwa-ke, izifo eziningi zabantu cishe ziholela ekubonakalisweni komtholampilo okuncane noma kungabikho nhlobo.

Ukudluliswa

I-Anaplasma phagocytophilum idluliselwa ngemikhaza ye-ixodid.E-United States ama-vector ayinhloko i-Ixodes scapularis ne-Ixodes pacificus, kuyilapho i-Ixode ricinus itholakale iyi-exophilic vector eyinhloko eYurophu.I-Anaplasma phagocytophilum isakazwa ngokudlulela yile mikhaza ye-vector, futhi abukho ubufakazi bokudluliselwa kwe-transovarial.Ucwaningo oluningi kuze kube manje oluphenye ukubaluleka kwezilwane ezincelisayo ze-A. phagocytophilum kanye nezindawo ezithwala imikhaza zigxile kumagundane kodwa lesi sidalwa sinezinhlobo eziningi zezilwane ezincelisayo, ezithelela amakati afuywayo, izinja, izimvu, izinkomo, namahhashi.

sgd

Ukuxilongwa

I-Indirect immunofluorescence assay ukuhlolwa okuyinhloko okusetshenziselwa ukuthola ukutheleleka.Amasampula e-serum yesigaba se-acute ne-convalescent angahlolwa ukuze kubhekwe ushintsho oluphindwe kane ku-antibody titer kuya ku-Anaplasma phagocytophilum.I-intracellular inclusions (morulea) ibonakala kuma-granulocyte ku-Wright noma ku-Gimsa enegazi elingcolisiwe.Izindlela ze-Polymerase chain reaction(PCR) zisetshenziselwa ukuthola i-Anaplasma phagocytophilum DNA.

Ukuvimbela

Awukho umgomo otholakalayo wokuvikela ukutheleleka kwe-Anaplasma phagocytophilum.Ukuvimbela kuncike ekuchayekeni kwe-ejenti yomkhaza (i-Ixodes scapularis, i-Ixodes pacificus, ne-Ixode ricinus) kusukela entwasahlobo kuya ekwindla, ukusetshenziswa kokuvimbela ama-antiacaricides, kanye nokusetshenziswa kwe-prophylactic ye-doxycycline noma i-tetracycline lapho uvakashela i-Ixodes scapularis, i-Ixodes pacide-ricinus ne-tick izifunda ezingapheli.

Ulwazi

I-Ehrlichia canis izinambuzane ezincane ezimise okwenduku ezisakazwa umkhaza wenja ensundu, i-Rhipcephalus sanguineus.I-E. canis iyimbangela ye-ehrlichiosis yakudala ezinjeni.Izinja zingangenwa yi-Ehrlichia spp eminingana.kodwa evame kakhulu ebangela i-canine ehrlichiosis i-E. canis.

I-E. canis manje yaziwa ukuthi isisakazekele kulo lonke elase-United States, eYurophu, eNingizimu Melika, e-Asia naseMedithera.

Izinja ezithelelekile ezingelashwa zingaba abathwali besifo iminyaka eminingi futhi ekugcineni zife ngenxa yokopha okukhulu.

ama-sdfs (2)
ama-sdfs (1)

Izimpawu

Ukutheleleka kwe-Ehrlichia canis ezinjeni kuhlukaniswe izigaba ezi-3;

ISIGABA ESIYI-ACUTE: Lesi ngokuvamile isigaba esithambile kakhulu.Inja ngeke isakwazi ukudla, ingadli, futhi kungenzeka ibe nama-lymph nodes akhulisiwe.Kungase kube nomkhuhlane futhi kodwa akuvamile ukuthi lesi sigaba sibulale inja.Iningi lizihlanza ngokwazo kodwa abanye bazodlulela esigabeni esilandelayo.

ISIGABA ESIPHANSI: Kulesi sigaba, inja ibonakala ijwayelekile.I-organism i-sequestered ku-spleen futhi empeleni ifihlekile lapho.

ISIGABA ESINGAPHELI: Kulesi sigaba inja iyagula futhi.Kufika ku-60% wezinja ezingenwe yi-E. canis zizopha ngendlela engavamile ngenxa yokuncipha kwezinombolo zamaplatelet.Ukuvuvukala okujulile emehlweni okubizwa ngokuthi "uveitis" kungase kwenzeke ngenxa yokuvuselela umzimba isikhathi eside.Imiphumela ye-Neurologic ingase ibonakale.

Ukuxilongwa nokwelashwa

Ukuxilongwa okuqondile kwe-Ehrlichia canis kudinga ukubonakala ngeso lengqondo kwe-morula ngaphakathi kwe-monocyte ku-cytology, ukutholwa kwamasosha omzimba e-E. canis serum ngokuhlolwa okungaqondile kwe-immunofluorescence antibody test (IFA), i-polymerase chain reaction (PCR) amplification, kanye/noma i-gel blotting (i-Western immunoblotting).

Umgomo oyinhloko wokuvimbela i-canine ehrlichiosis ukulawula imikhaza.Umuthi okhethwayo wokwelapha zonke izinhlobo ze-ehrlichiosis yi-doxycycline okungenani inyanga eyodwa.Kufanele kube nokuthuthuka okumangalisayo komtholampilo kungakapheli amahora angama-24-48 kulandela ukuqaliswa kokwelashwa ezinjeni ezinesigaba esibucayi noma esibuthakathaka sesigaba esingamahlalakhona.Ngalesi sikhathi, izibalo zamaplatelet ziqala ukwanda futhi kufanele zibe ngokwejwayelekile phakathi nezinsuku eziyi-14 ngemuva kokuqala kokwelashwa.

Ngemuva kokutheleleka, kungenzeka ukuthi uphinde utheleleke;ukuzivikela komzimba akuhlali ngemva kokutheleleka kwangaphambilini.

Ukuvimbela

Ukuvimbela okungcono kakhulu kwe-ehrlichiosis ukugcina izinja zingenayo imikhaza.Lokhu kufanele kufake phakathi ukuhlola isikhumba nsuku zonke ukuze uthole imikhaza nokwelapha izinja ngokulawula imikhaza.Njengoba imikhaza ithwala ezinye izifo ezibhubhisayo, njengesifo i-Lyme, i-anaplasmosis kanye ne-Rocky Mountain spotted fever, kubalulekile ukugcina izinja zingenayo imikhaza.

Ulwazi

I-Leishmaniasis yisifo esiyingozi kakhulu futhi esibi kakhulu se-parasitic kubantu, izinja kanye nezinsikazi.I-ejenti ye-leishmaniasis i-protozoan parasite futhi ingeye-leishmania donovani complex.Lesi sitshalo sisatshalaliswa kabanzi emazweni ashisayo naseNingizimu Yurophu, e-Afrika, e-Asia, eNingizimu Melika naseMelika Ephakathi.I-Leishmania donovani infantum (L. infantum) ibhekene nesifo se-feline kanye ne-canine eNingizimu Yurophu, e-Afrika, nase-Asia.I-Canine Leishmaniasis yisifo esiqhubekayo sesistimu.Akuzona zonke izinja eziba nesifo somtholampilo ngemva kokugonywa nama-parasites.Ukuthuthukiswa kwesifo somtholampilo kuncike ohlotsheni lokusabela komzimba isilwane ngasinye esinakho

ngokumelene nama-parasites.

Izimpawu

E-Canine

Kokubili ukubonakaliswa kwe-visceral kanye ne-cutaneous kungase kutholakale ngesikhathi esisodwa ezinjeni;ngokungafani nabantu, ama-syndromes ahlukene e-cutaneous kanye ne-visceral awabonwa.Izimpawu zomtholampilo ziyahlukahluka futhi zingalingisa ezinye izifo.Ukutheleleka nge-asymptomatic nakho kungenzeka.Izimpawu ezivamile ze-visceral zingase zihlanganise imfiva (engase ibe ngezikhathi ezithile), i-anemia, i-lymphadenopathy, i-splenomegaly, ukukhathala, ukuncipha kokubekezelela ukuvivinya umzimba, ukuncipha kwesisindo, nokuncipha kwesifiso sokudla.Izimpawu ezivamile ze-visceral zihlanganisa isifo sohudo, ukuhlanza, i-melena, i-glomerulonephritis, ukwehluleka kwesibindi, i-epistaxis, i-polyuria-polydipsia, ukuthimula, ukuxhwala (ngenxa ye-polyarthritis noma i-myositis), i-ascites, kanye ne-colitis engapheli.

Ku-Feline

Amakati awavamile ukungenwa yilesi sifo.Emakatini amaningi angenwe yileli gciwane, izilonda zikhawulelwe ezilonda zesikhumba ezinoqweqwe, ngokuvamile ezitholakala ezindebeni, emakhaleni, ezinkopheni, noma ezindebeni.Izilonda ze-Visceral nezimpawu azivamile.

Umjikelezo wokuphila

Umjikelezo wempilo uqedwa ngamahosti amabili.Umsingathi wezilwane ezinomgogodla kanye nesilwane esingenamgogodla (impukane yesihlabathi).Impukane yesihlabathi yesifazane idla isilwane esinezilwane ezinomgogodla futhiidla amastigotes.Ama-promastigote ane-flagellated akhula ezinambuzaneni.Ama-promastigote ajovwa kusilwane esiphila nomgogodla ngesikhathi sokuphakelwa kwe-sandfly.Ama-promastigote akhula abe amastigote futhi aphindaphindeke ngokuyinhloko kuma-macrophages.Ukuphindaphindeka ngaphakathi kwama-macrophages esikhumba, i-mucosa kanye ne-viscera, kubangela i-cutaneous, mucosal kanye ne-visceral leishmaniasis ngokulandelana.

sazxxz1

Ukuxilongwa

Ezinjeni, i-leishmaniasis ivamise ukutholakala ngokubhekwa ngqo kwezimuncagazi, kusetshenziswa i-Giemsa noma amabala asheshayo okuphathelene, kuma-smear asuka kuma-lymph node, ubende, noma ama-aspirates omnkantsha, ama-tissue biopsies, noma ukuklwebheka kwesikhumba ezilonda.Izinto eziphilayo zingase futhi zitholakale ezilonda ze-ocular, ikakhulukazi kuma-granulomas.Ama-astigote ayindilinga kuya kuma-oval parasites, anenucleus eyindilinga ye-basophilic kanye ne-kinetoplast encane efana nenduku.Atholakala kuma-macrophages noma akhululwe kumaseli aphukile.Amasu we-Immunohistochemistry kanye ne-polymerase chain reaction (PCR) nawo asetshenziswa.

Ukuvimbela

Izidakamizwa ezisetshenziswa kakhulu yilezi: I-Meglumine Antimoniate ehlotshaniswa ne-Allopurinol, i-Aminosidine, futhi muva nje, i-Amphotericin B. Yonke le mithi idinga uhlobo lwemithamo eminingi, futhi lokhu kuzoncika esimweni sesiguli kanye nokubambisana komnikazi.Kuphakanyiswa ukuthi ukwelashwa kwesondlo kufanele kugcinwe nge-allopurinol, ngoba akunakwenzeka ukuqinisekisa ukuthi izinja ngeke ziphinde zibuyele uma ukwelashwa kuyekwa.Ukusetshenziswa kwamakholomu aqukethe ama-insecticides, ama-shampoos noma izifutho ezisebenzayo ukuvikela izinja ekulunyweni yi-sandfly kumele kusetshenziswe ngokuqhubekayo kuzo zonke iziguli ezilashwayo.Ukulawulwa kwe-vector kungenye yezinto ezibaluleke kakhulu zokulawula izifo.

I-sandfly isengozini yezibulala-zinambuzane ezifanayo ne-malaria.

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