I-Leishmania Ab Test Kit | |
Inombolo yekhathalogi | I-RC-CF24 |
Isifinyezo | Ukutholwa kwamasosha omzimba athile eLeishmaniaphakathi nemizuzu eyi-10 |
Isimiso | Isinyathelo esisodwa sokuhlolwa kwe-immunochromatographic |
Okuhloswe ngakho Ukuthola | L. chagasi, L. infantum, kanye nama-antiboies e-L. donovani |
Isampula | Igazi le-Canine lonke, i-serum noma i-plasma |
Isikhathi sokufunda | 5 ~ 10 imizuzu |
Ukuzwela | 98.9 % vs. IFA |
Ukucaciswa | 100.0 % vs. IFA |
Umkhawulo Wokutholwa | I-IFA Titer 1/32 |
Ubuningi | Ibhokisi elingu-1 (ikhithi) = amadivaysi ayi-10 (Ukupakishwa komuntu ngamunye) |
Okuqukethwe | Ikhithi yokuhlola, ibhodlela le-Buffer, kanye nezinto ezilahlwayo |
Isitoreji | Ithempelesha Yegumbi (ku-2 ~ 30℃) |
Ukuphelelwa yisikhathi | Izinyanga ezingama-24 ngemuva kokukhiqiza |
Isexwayiso | Sebenzisa phakathi kwemizuzu eyi-10 ngemva kokuvula Sebenzisa inani elifanele lesampula (0.01 ml yedrophu) Sebenzisa ngemva kwemizuzu eyi-15~30 e-RT uma egcinwe ngaphansi kwezimo ezibandayo Cabanga ngemiphumela yokuhlolwa njengengavumelekile ngemva kwemizuzu eyi-10. |
I-Leishmaniasis yisifo esiyingozi kakhulu futhi esibi kakhulu se-parasitic kubantu, izinja kanye nezinsikazi.I-ejenti ye-leishmaniasis i-protozoan parasite futhi ingeye-leishmania donovani complex.Lesi sitshalo sisatshalaliswa kabanzi emazweni ashisayo naseNingizimu Yurophu, e-Afrika, e-Asia, eNingizimu Melika naseMelika Ephakathi.I-Leishmania donovani infantum (L. infantum) ibhekene nesifo se-feline kanye ne-canine eNingizimu Yurophu, e-Afrika, nase-Asia.I-Canine Leishmaniasis yisifo esiqhubekayo sesistimu.Akuzona zonke izinja eziba nesifo somtholampilo ngemva kokugonywa nama-parasites.Ukuthuthukiswa kwesifo somtholampilo kuncike ohlotsheni lokusabela komzimba isilwane ngasinye esinakho
ngokumelene nama-parasites.
E-Canine
Kokubili ukubonakaliswa kwe-visceral kanye ne-cutaneous kungase kutholakale ngesikhathi esisodwa ezinjeni;ngokungafani nabantu, ama-syndromes ahlukene e-cutaneous kanye ne-visceral awabonwa.Izimpawu zomtholampilo ziyahlukahluka futhi zingalingisa ezinye izifo.Ukutheleleka nge-asymptomatic nakho kungenzeka.Izimpawu ezivamile ze-visceral zingase zihlanganise imfiva (engase ibe ngezikhathi ezithile), i-anemia, i-lymphadenopathy, i-splenomegaly, ukukhathala, ukuncipha kokubekezelela ukuvivinya umzimba, ukuncipha kwesisindo, nokuncipha kwesifiso sokudla.Izimpawu ze-visceral ezingavamile zihlanganisa isifo sohudo, ukuhlanza, i-melena, i-glomerulonephritis,
ukwehluleka kwesibindi, i-epistaxis, i-polyuria-polydipsia, ukuthimula, ukuxhwala (ngenxa ye-
i-polyarthritis noma i-myositis), i-ascites, ne-colitis engapheli.
Ku-Feline
Amakati awavamile ukungenwa yilesi sifo.Emakatini amaningi angenwe yileli gciwane, izilonda zikhawulelwe ezilonda zesikhumba ezinoqweqwe, ngokuvamile ezitholakala ezindebeni, emakhaleni, ezinkopheni, noma ezindebeni.Izilonda ze-Visceral nezimpawu azivamile.
Umjikelezo wempilo uqedwa ngamahosti amabili.Umsingathi wezilwane ezinomgogodla kanye nesilwane esingenamgogodla (i-sandfly).Impukane yesihlabathi yesifazane idla izilwane ezinomgogodla futhi idla ama-astigote.Ama-promastigote ane-flagellated akhula ezinambuzaneni.Ama-promastigote ajovwa esilwaneni esinezilwane ezinomgogodla ngesikhathi sokuphakelwa kwe-sandfly.Ama-promastigote akhula abe amastigote futhi aphindaphindeke ngokuyinhloko kuma-macrophages.Ukuphindaphindeka ngaphakathi kwama-macrophages we-
isikhumba, i-mucosa kanye ne-viscera, kubangela i-leishmaniasis ye-cutaneous, mucosal kanye ne-visceral leishmaniasis ngokulandelanayo.
Ezinjeni, i-leishmaniasis ivamise ukutholakala ngokubhekwa ngqo kwezimuncagazi, kusetshenziswa i-Giemsa noma amabala asheshayo okuphathelene, kuma-smear asuka kuma-lymph node, ubende, noma ama-aspirates omnkantsha, ama-tissue biopsies, noma ukuklwebheka kwesikhumba ezilonda.Izinto eziphilayo zingase futhi zitholakale ezilonda ze-ocular, ikakhulukazi kuma-granulomas.Ama-astigote ayindilinga kuya kuma-oval parasites, anenucleus eyindilinga ye-basophilic kanye ne-kinetoplast encane efana nenduku.Atholakala kuma-macrophages noma akhululwe kumaseli aphukile.I-Immunohistochemistry kanye ne-polymerase chain reaction (PCR)
kusetshenziswa namasu.
Izidakamizwa ezisetshenziswa kakhulu yilezi: I-Meglumine Antimoniate ehlotshaniswa ne-Allopurinol, i-Aminosidine, futhi muva nje, i-Amphotericin B. Yonke le mithi idinga uhlobo lwemithamo eminingi, futhi lokhu kuzoncika esimweni sesiguli kanye nokubambisana komnikazi.Kuphakanyiswa ukuthi ukwelashwa kwesondlo kufanele kugcinwe nge-allopurinol, ngoba akunakwenzeka ukuqinisekisa ukuthi izinja ngeke ziphinde zibuyele uma ukwelashwa kuyekwa.Ukusetshenziswa kwamakholomu aqukethe ama-insecticides, ama-shampoos noma izifutho ezisebenzayo ukuvikela izinja ekulunyweni yi-sandfly kumele kusetshenziswe ngokuqhubekayo kuzo zonke iziguli ezilashwayo.Ukulawulwa kwe-vector kungenye yezinto ezibaluleke kakhulu zokulawula izifo.
I-sandfly isengcupheni yokubulala izinambuzane ezifanayo ne-malaria.